For over 20 years, the Brueckner Lab has explored the overall theme of cilia and cardiogenesis, making impactful findings ranging from basic research to patient studies.

As a physician-scientist, Dr. Martina Brueckner has spent her entire career caring for patients with congenital heart disease (CHD) while elucidating the causal mechanisms through employing genetics, animal models and cell-based approaches in her lab. Our goal as a lab is to advance our understanding of CHD etiology by combining classic developmental cell biology and cutting-edge large-scale genomics with Dr. Brueckner’s continued involvement in clinical pediatric cardiology.